But this survey suggests that alprazolam may be riskier than diazepam, lorazepam, or clonazepam. For example, every clinician knows the hazards of oversedation when benzodiazepines or carisoprodol is used with an opioid. It points out that this specific combination may be the most dangerous of all opioid combinations. This is important and practical information. Hydrocodone (Vicodin, Lortab, Norco, Lorcet).1 He studied the drug ingestions reported to the Texas Poison Center between 19 and found that 1,295 cases overdosed on a single drug combination of three different drugs: Nevertheless, opioid overdoses are something every prescriber must consider and attempt to prevent.Ī recent article by Mathias B. In addition, almost all of the overdoses have been persons who illegally obtained prescription opioids and/or failed to take them as prescribed. Compared with the overall number of people who have been helped, only a tiny percentage have overdosed. In reality, about 3% of the US population, or about 10 million people, have been prescribed opioids in recent years. Admittedly, all the anti-opioid, anti-MD, and anti-pain treatment propaganda being generated these days is a little overdone. By now, just about everybody has heard plenty about all of the prescription opioid overdoses and deaths.
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